1.2 Metabolite Knockout Landscape
=====================================
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from bokeh.io import output_notebook
output_notebook()
.. raw:: html
.. code:: ipython3
from cameo import models
from marsi.cobra.flux_analysis import metabolite_knockout_fitness
Metabolite Knockout Landscape
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
This method is used to provide an overview of how different metabolite
knockouts change the fitness of the model. The simulations can be run
with different methods: fba, moma, room, etc.
.. code:: ipython3
model = models.bigg.iJO1366
.. code:: ipython3
result = metabolite_knockout_fitness(model, progress=True, objective=model.reactions.BIOMASS_Ec_iJO1366_core_53p95M)
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result
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.. parsed-literal::